*TIME SLOTS LISTED BELOW ARE EDT!!! 

Thursday, June 13 2024

Talk Title 

Speaker

Company

Time

EDT

Registration   

   

7:30 - 8:30

Conference Opening

   

8:30 - 8:40

SESSION I: Complex Models to Support Drug Development

Chairs: Mitesh Patel, Novartis & Ruchia Duggal, Merck

Session I Opening Remarks 

8:40 - 8:45

Plenary Lecture: BBB organoids (spheroids) for drug delivery to the brain + PET imaging - Title TBA Choi-Fong Cho Brigham and Women's Hospital, Harvard Medical School

8:45 - 9:25

Organotypic Slice Cultures as a Model System to Understand Lipid Nanoparticle Delivery

Hema Muralidharan

Moderna

9:25 - 9:55

Liver MPS Model Comparison for Clearance IVIVC

Birk Poller

Novartis, Basel

9:55 - 10:25

Overcoming limitations of Caco-2 cells for ADME using adult human crypt-derived planar intestinal epithelium cultures Ben Scruggs  Altis Biosystems  10:25 - 10:55
Break    

10:55 - 11:15

Plenary Speaker Introduction Vinayak Hosagrahara  Nimbus Therapeutics  11:15 - 11:20
Plenary Lecture: ADMET In The Age of AI Daniel Price Nimbus Therapeutics

11:20 - 12:00

Fatty Liver Disease Modeling In a Micropatterned Primary Hepatocyte Co-culture (HEPATOPAC): Applications In Drug Development & Screening Karissa Cottier

12:00 - 12:25

Lunch    

12:25 - 1:35

Vendor Talk TBD  

1:35 - 1:45

SESSION II: PK/PD for New Modalities

Chairs: Steven Louie, Moderna & Dallas Bednarczyk, Novartis

Session II Opening Remarks 

1:45 - 1:50

Use of PK/PD Modeling to Understand the Potential and Pitfalls of New Modalities- Picking the Winners from the Losers  Alison Betts Takeda

1:50 - 2:20

PK/PD models for glue degraders for BBB, CNS target - Title TBA TK Phung Novartis

2:20 - 2:50

LNP's - Title TBA Christopher Rowbottom Moderna

2:50- 3:20

Break    

3:20 - 3:40

SESSION III: Advanced Tools to Support Drug Discovery & Development

Chairs: Joseph Tillotson, Pfizer & Seema Chauhan Kumar, Pioneering Medicines 

Session III Opening Remarks 

3:40 - 3:45

Measurement of Target Exposure and Binding with Positron Emission Tomography (PET) Imaging in Drug Research and Development Laigao Chen Pfizer

3:45 - 4:15

Title TBA Jonathan Jackson Pfizer

4:15 - 4:45

Closing Remarks

   

4:45- 4:50

Reception

   

4:50- 5:50

Workshops

Session I: Complex Models to Support Drug Development

Session II: PK/PD of New Modalities

Session III: Advanced Tools to Support Drug Discovery and Development

 

Registration

Click here to register for the NE-ADME conference online.

NE-ADME 2024 will take place June 13, 2024

Merck, Boston, MA

 

The Boston Society

The Boston Society (R) is an internationally-recognized NON-PROFIT organization dedicated to bringing the best scientific ideas to industrial practice through focused, timely workshops and conferences. 501(c)3

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