NE-ADME 2024 Agenda
NE-ADME 2024 Conference Program
*Speakers and titles are subject to change. Updated 06/10/2024
*TIME SLOTS LISTED BELOW ARE EDT!!!
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Thursday, June 13 2024 |
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| Talk Title |
Speaker |
Company |
Time EDT |
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Registration |
7:30 - 8:30 |
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Conference Opening and Plenary Lecture Introduction |
Mitesh Patel | Novartis |
8:30 - 8:40 |
| Plenary Lecture: ECCS Class 3A: Interaction of Gabapentin and Its Analogues with Transporters - A Love-Hate Relationship | Ayman El-Kattan | IFM Therapeutics |
8:40 - 9:20 |
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SESSION I: Complex Models to Support Drug Development Chairs: Mitesh Patel, Novartis & Ruchia Duggal, Merck |
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| Session I Opening Remarks |
9:42 - 9:25 |
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| Utilizing Ex Vivo Liver Slice Models for Preclinical Evaluation of LNP-Based mRNA Delivery |
Hema Muralidharan |
Moderna |
9:25 - 9:55 |
| Liver MPS Model Comparison for Clearance IVIVC |
Birk Poller |
Novartis, Basel |
9:55 - 10:25 |
| Overcoming Limitations of Caco-2 Cells for ADME Using Adult Human Crypt-Derived Planar Intestinal Epithelium Cultures | Ben Scruggs | Altis Biosystems | 10:25 - 10:55 |
| Break |
10:55 - 11:15 |
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| Plenary Speaker Introduction | Vinayak Hosagrahara | Nimbus Therapeutics | 11:15 - 11:20 |
| Plenary Lecture: ADMET In The Age of AI | Daniel Price | Nimbus Therapeutics |
11:20 - 12:00 |
| Fatty Liver Disease Modeling In a Micropatterned Primary Hepatocyte Co-culture (HEPATOPAC): Applications In Drug Development & Screening | Karissa Cottier |  |
12:00 - 12:25 |
| Lunch |
12:25 - 1:35 |
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| Cryo-Fluorescence Tomography: Transformative 3D Imaging to Monitor Drug PK/PD | Matt Silva |  |
1:35 - 1:45 |
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SESSION II: PK/PD for New Modalities Chairs: Steven Louie, Moderna & Dallas Bednarczyk, Novartis |
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| Session II Opening Remarks |
1:45 - 1:50 |
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| Use of PK/PD Modeling to Understand the Potential and Pitfalls of New Modalities- Picking the Winners from the Losers | Alison Betts | Takeda |
1:50 - 2:20 |
| Dynamical Modeling of Protein Degradation to Improve Compound Selection in Drug Discovery | TK Phung | Novartis |
2:20 - 2:50 |
| Pharmacokinetics and Distribution of Lipid Nanoparticles | Christopher Rowbottom | Moderna |
2:50- 3:20 |
| Break |
3:20 - 3:40 |
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SESSION III: Advanced Tools to Support Drug Discovery & Development Chairs: Joseph Tillotson, Pfizer & Seema Chauhan Kumar, Pioneering Medicines |
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| Session III Opening Remarks |
3:40 - 3:45 |
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| Measurement of Target Exposure and Binding with Positron Emission Tomography (PET) Imaging in Drug Research and Development | Laigao Chen | Pfizer |
3:45 - 4:15 |
| Early Drug-Induced Liver Injury Risk Screening: “Free,” as Good as it Gets | Jonathan Jackson | Pfizer |
4:15 - 4:45 |
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Closing Remarks |
Seema Chauhan Kumar | Pioneering Medicines |
4:45- 4:50 |
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Reception |
4:50- 5:50 |
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