NE-ADME 2025 Agenda
NE-ADME 2025 Conference Program Download
*Speakers and titles are subject to change. Updated 05/27/2025
*TIME SLOTS LISTED BELOW ARE EDT!!!
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Wednesday, June 11 2025 |
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| Talk Title |
Speaker |
Company |
Time EDT |
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Registration & Breakfast |
7:30 - 8:30 |
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Conference Opening and Plenary Lecture Introduction |
Seema Kumar | Pioneering Medicines |
8:30 - 8:40 |
| Plenary Lecture: Blood-Brain-Barrier Assembloids For Modeling Therapeutic Delivery to Brain Tumors | Choi-Fong Cho | Harvard University |
8:40 - 9:20 |
| Sponsor Talk - Applications of Cryopreserved Plateable Mouse Hepatocytes in Drug Metabolism and Gene Regulation Discovery Studies | Erik Willems |  |
9:20 - 9:30 |
| Speaker Intro: Steven Louie, Medicilon |
9:30 - 9:35 |
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| Disposition of Novel Brain-Penetrant Therapeutics |
Cinthia Pastuskovas |
Denali Therapeutics |
9:35 - 10:05 |
| Break |
10:05 - 10:30 |
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| Speaker Intro:Dallas Bednarczyk, Novartis |
10:30 - 10:35 |
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| Predicting Oral Absorption, Intestinal Availability, CYP3A4 Induction and Transporter-mediated Drug-Drug Interactions Using Human Primary Intestinal 3D Model (EpiIntestinalTM) |
Paresh Chothe |
AstraZeneca |
10:35 - 11:05 |
| Speaker Intro: Vinayak Hosagrahara, Enveda Bio | 11:05 - 11:10 | ||
| Highlights From the Final ICH M12 Guideline "Drug Interaction Studies" - What's Changed and Considerations for Your IND Programs | Brian Ogilvie | BioIVT | 11:10 - 11:40 |
| Speaker Intro: | Pei Li | Vertex | 11:40 - 11:45 |
| Sponsor Talk: Cryo-Fluorescence Tomography: Transformative 3D Imaging to Monitor Drug PK/PD | Matt Silva |  |
11:45 - 12:10 |
| Lunch |
12:10 - 1:20 |
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| Speaker Intro: | Maria Fitzgerald | Ipsen |
1:20 - 1:25 |
| Sponsor Talk - Advancing siRNA from Discovery Target to Preclinical Candidate | Dr. Qingcong Lin |  |
1:25 - 1:35 |
| Speaker Intro: Seema Kumar, Flagship Pioneering |
1:35 - 1:40 |
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| AI/ML for Model-Informed Precision Medicine | Nadia Terranova | EMD Serono (Merck KGaA) |
1:40 - 2:10 |
| Speaker Intro: | Chris Rowbottom | Moderna |
2:10 - 2:15 |
| Immunogenicity Risk Assessment Strategies Across Modalities: Regulatory-Driven Approaches for Clinical Development | Jason DelCarpini | Moderna Therapeutics |
2:15 - 2:45 |
| Break |
2:45 - 3:10 |
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| Speaker Intro | Ruchia Duggal | Merck |
3:10 - 3:15 |
| Strategies and Approaches for Modeling and Prediction of Large Molecule Drug-Drug Interactions | Jaydeep Yadav | Merck |
3:15- 3:45 |
| Speaker Intro: Joseph Tillotson, Pfizer |
3:45 - 3:50 |
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| DMPK-on-a-Chip: Developing an Organ-Linked MPS System to Inform Human Pharmacokinetics | James Gosset | Pfizer |
3:50 - 4:20 |
| Speaker Intro | Dallas Bednarczyk | Novartis |
4:20 - 4:25 |
| Harnessing in vitro and Bioanalytical Data for Quantitative Systems Pharmacology (QSP) Modeling of Antibody-Drug Conjugates | Eshita Khera | Novartis |
4:25 - 4:55 |
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Closing Remarks |
Joseph Tillotson | Pfizer |
4:55- 5:00 |
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Reception |
5:00- 6:00 |
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